Ammonium Chloride
CAS No. 12125-02-9
Ammonium Chloride( —— )
Catalog No. M35833 CAS No. 12125-02-9
Ammonium chloride acts as a small molecule autophagy inhibitor.Ammonium chloride is a pH-regulating, heteropolar compound that can cause intracellular alkalosis and metabolic acidosis, thereby affecting enzyme activity and influencing processes in biological systems.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 50 | In Stock |
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| 1G | 72 | In Stock |
|
Biological Information
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Product NameAmmonium Chloride
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NoteResearch use only, not for human use.
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Brief DescriptionAmmonium chloride acts as a small molecule autophagy inhibitor.Ammonium chloride is a pH-regulating, heteropolar compound that can cause intracellular alkalosis and metabolic acidosis, thereby affecting enzyme activity and influencing processes in biological systems.
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DescriptionAmmonium chloride, for molecular biology (Salmiac, for molecular biology) is ammonium chloride that can be used for molecular biology research. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride acts as an autophagy inhibitor.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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RecptorAutophagy | Antifungal
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Research Area——
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Indication——
Chemical Information
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CAS Number12125-02-9
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Formula Weight53.49
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Molecular FormulaClH4N
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Purity>98% (HPLC)
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Solubility——
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SMILESN.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Lys05
Lys05 (Lys01 trihydrochloride, PS-1001)?is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ); shows IC50 values of 3.6, 3.8, 6 and 7.9 uM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay.
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Hemin
Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.
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Talarozole
Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM respectively.Talarozole for the treatment of acne psoriasis and other keratinization disorders.
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